Synthesis of 5,7-dichloro-2-adamantanone

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Abstract

The reaction of 2-adamantanecarboxylic acid with an excess of chlorine in the presence of AlCl3 under heating gave 5,7-dichloro-2-adamantanecarboxylic acid. This product was sequentially introduced into the Curtius, deamination, and oxidation reactions to form 5,7-dichloro-2-adamantanone. The resulting product is a key substrate for synthesis of new substances and materials with a set of practically important properties, including both the synthesis of biologically active molecules and systems for chemiluminescent diagnostic methods.

About the authors

M. Yu. Skomorokhov

Samara State Technical University

Email: ivleva.ea@samgtu.ru

M. S Zaborskaya

Samara State Technical University

Email: ivleva.ea@samgtu.ru

E. A Ivleva

Samara State Technical University

Email: ivleva.ea@samgtu.ru

A. K Shiryaev

Samara State Technical University

Email: ivleva.ea@samgtu.ru

Yu. N. Klimochkin

Samara State Technical University

Email: ivleva.ea@samgtu.ru

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