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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Clinical Practice</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Clinical Practice</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиническая практика</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2220-3095</issn><issn publication-format="electronic">2618-8627</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">33946</article-id><article-id pub-id-type="doi">10.17816/clinpract33946</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Difficulties in treatment of acute coronary syndrome in a patient with end-stage chronic renal failure on program hemodialysis (case description)</article-title><trans-title-group xml:lang="ru"><trans-title>Трудности лечения острого коронарного синдрома у пациента с терминальной стадией хронической почечной недостаточности на программном гемодиализе (описание случая)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6027-2898</contrib-id><contrib-id contrib-id-type="spin">6073-1445</contrib-id><name-alternatives><name xml:lang="en"><surname>Bocharov</surname><given-names>Aleksandr V.</given-names></name><name xml:lang="ru"><surname>Бочаров</surname><given-names>Александр Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><email>bocharovav@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sidorov</surname><given-names>Denis V.</given-names></name><name xml:lang="ru"><surname>Сидоров</surname><given-names>Денис Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>denis.sidorov1972@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0530-3268</contrib-id><name-alternatives><name xml:lang="en"><surname>Popov</surname><given-names>Leonid V.</given-names></name><name xml:lang="ru"><surname>Попов</surname><given-names>Леонид Валентинович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>popovcardio@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kostroma Regional Clinical Hospital named after Korolev E.I.</institution></aff><aff><institution xml:lang="ru">Костромская областная клиническая больница имени Королева Е.И.</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">National Medical and Surgical Center named after N.I. Pirogov</institution></aff><aff><institution xml:lang="ru">Национальный медико-хирургический центр имени Н.И. Пирогова</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2020-09-14" publication-format="electronic"><day>14</day><month>09</month><year>2020</year></pub-date><pub-date date-type="pub" iso-8601-date="2020-10-23" publication-format="electronic"><day>23</day><month>10</month><year>2020</year></pub-date><volume>11</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>102</fpage><lpage>106</lpage><history><date date-type="received" iso-8601-date="2020-04-29"><day>29</day><month>04</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-08-31"><day>31</day><month>08</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Bocharov A.V., Sidorov D.V., Popov L.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, Бочаров А.В., Сидоров Д.В., Попов Л.В.</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Bocharov A.V., Sidorov D.V., Popov L.V.</copyright-holder><copyright-holder xml:lang="ru">Бочаров А.В., Сидоров Д.В., Попов Л.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://clinpractice.ru/clinpractice/article/view/33946">https://clinpractice.ru/clinpractice/article/view/33946</self-uri><abstract xml:lang="en"><p><bold>Background</bold>. The surgical treatment of the coronary heart disease (acute coronary syndrome) in patients undergoing program hemodialysis has its own characteristics, which are not fully reflected in the cardiological recommendations. In particular, coronary artery bypass grafting is preferable to stenting, the drug of choice among p2y12 platelet receptor blockers is clopidogrel, with the infeasibility of rosuvastatin prescription. All these points are often ignored by treating doctors from the cardiology team when choosing the optimal treatment strategy for patients in this group.</p> <p><bold>Description of the clinical case</bold>. The article presents a case of treating acute coronary syndrome in a patient undergoing program hemodialysis. The problems of coronary revascularization and the drug therapy in this category of patients are discussed, and the ways to solve them are shown by the example of this clinical case.</p> <p><bold>Conclusion</bold>. In special cases, such as acute coronary syndrome in patients with chronic renal failure who are on program hemodialysis, the endovascular treatment strategy should be considered only if the specifics of the prescribed pharmacotherapy are taken into account.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование</bold>. Хирургическое лечение ишемической болезни сердца (острого коронарного синдрома) у больных, находящихся на программном гемодиализе, имеет свои особенности, которые не в полной мере отражены в кардиологических рекомендациях. В частности, аортокоронарное шунтирование — более предпочтительный метод, чем стентирование; препаратом выбора среди блокаторов P2Y12-рецепторов тромбоцитов является клопидогрел при невозможности назначения розувастатина. Все эти моменты достаточно часто игнорируются лечащими врачами — участниками кардиокоманды при выборе оптимальной стратегии лечения пациентов данной группы.</p> <p><bold>Описание клинического случая</bold>. В статье представлен случай лечения острого коронарного синдрома у пациента, находящегося на программном гемодиализе. Обсуждаются проблемы реваскуляризации коронарного русла и медикаментозной терапии у данной категории больных, показаны пути их решения на примере данного клинического случая.</p> <p><bold>Заключение</bold>. В особых случаях, например при остром коронарном синдроме, у пациентов с хронической почечной недостаточностью, находящихся на программном гемодиализе, следует рассматривать эндоваскулярную стратегию лечения только при соблюдении особенностей назначаемой фармакотерапии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>acute coronary syndrome</kwd><kwd>hemodialysis</kwd><kwd>end-stage renal disease</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>острый коронарный синдром</kwd><kwd>гемодиализ</kwd><kwd>терминальная стадия почечной недостаточности</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Neumann FJ, Sousa-Uva M, Ahlsson A, et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. 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