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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Clinical Practice</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Clinical Practice</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиническая практика</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2220-3095</issn><issn publication-format="electronic">2618-8627</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">609557</article-id><article-id pub-id-type="doi">10.17816/clinpract609557</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Научные обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The methods of perfecting the surface of titanium alloy-based endoprostheses used in pediatric oncology</article-title><trans-title-group xml:lang="ru"><trans-title>Методы усовершенствования поверхности эндопротезов на основе титановых сплавов, применяемых в детской онкопедиатрии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1237-0802</contrib-id><name-alternatives><name xml:lang="en"><surname>Gorokhova</surname><given-names>Elizaveta K.</given-names></name><name xml:lang="ru"><surname>Горохова</surname><given-names>Елизавета Константиновна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>elizavetagorokhova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1063-6590</contrib-id><contrib-id contrib-id-type="spin">2202-2448</contrib-id><name-alternatives><name xml:lang="en"><surname>Markov</surname><given-names>Nikolay M.</given-names></name><name xml:lang="ru"><surname>Марков</surname><given-names>Николай Михайлович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><email>markovnm@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4451-3233</contrib-id><name-alternatives><name xml:lang="en"><surname>Grachev</surname><given-names>Nikolai S.</given-names></name><name xml:lang="ru"><surname>Грачев</surname><given-names>Николай Сергеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><email>nick-grachev@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7600-6191</contrib-id><contrib-id contrib-id-type="spin">6341-8912</contrib-id><name-alternatives><name xml:lang="en"><surname>Lopatin</surname><given-names>Andrey V.</given-names></name><name xml:lang="ru"><surname>Лопатин</surname><given-names>Андрей Вячеславович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><email>and-lopatin@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3932-6257</contrib-id><contrib-id contrib-id-type="spin">6155-9348</contrib-id><name-alternatives><name xml:lang="en"><surname>Vorozhtsov</surname><given-names>Igor N.</given-names></name><name xml:lang="ru"><surname>Ворожцов</surname><given-names>Игорь Николаевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>Dr.Vorozhtsov@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2438-1202</contrib-id><contrib-id contrib-id-type="spin">1719-7756</contrib-id><name-alternatives><name xml:lang="en"><surname>Dudaeva</surname><given-names>Anna A.</given-names></name><name xml:lang="ru"><surname>Дудаева</surname><given-names>Анна Ахмедовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>dudaeva.dr@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии имени Дмитрия Рогачева</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-10-02" publication-format="electronic"><day>02</day><month>10</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2024-11-02" publication-format="electronic"><day>02</day><month>11</month><year>2024</year></pub-date><volume>15</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>68</fpage><lpage>74</lpage><history><date date-type="received" iso-8601-date="2023-10-16"><day>16</day><month>10</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2024-08-07"><day>07</day><month>08</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Эко-Вектор</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://clinpractice.ru/clinpractice/article/view/609557">https://clinpractice.ru/clinpractice/article/view/609557</self-uri><abstract xml:lang="en"><p>The rehabilitation of pediatric patients with oncology diseases localized in the maxillofacial area is a complex and long-term process. Most frequently, the resection area involves the maxilla or the mandible, which, in turn, impairs the functioning of the whole dentofacial system. The restoration of the integrity of the facial structures is the key task in the treatment of such patients. One of the main materials used for reconstructing the jaws is the titanium alloy. However, despite its beneficial properties and characteristics, there is a high risk of inflammation, encapsulation or failure of the endoprosthesis. The aim of the research was to analyze the data available up to date on the methods of perfecting the surfaces of titanium endoprostheses based on the published research works. After analyzing the articles devoted to the modification of the surface of titanium constructions used for endoprosthetics, for the period from 2008 until 2022 (n=41), we came to a conclusion that the modification of the surface of titanium endoprostheses results in an increase in its osteointegration, which decreases the risks of failure for the constructions.</p></abstract><trans-abstract xml:lang="ru"><p>Реабилитация пациентов детского возраста с онкопатологией, локализованной в челюстно-лицевой области, — сложный и длительный процесс. Чаще всего резекция затрагивает верхнюю или нижнюю челюсть, что в свою очередь нарушает функционирование всей зубочелюстной системы. Восстановление целостности лицевых структур является ключевой задачей при лечении таких пациентов. Одним из основных материалов для реконструкции челюсти является сплав титана. Однако, несмотря на его положительные свойства и характеристики, велик риск воспаления, инкапсуляции и отторжения эндопротеза. Целью исследования был анализ существующих на сегодняшний день данных по методикам усовершенствования поверхности титановых эндопротезов на основании опубликованных работ. Проанализировав статьи по модификации поверхности конструкций из титана, применяемых для эндопротезирования, за период с 2008 по 2022 год (n=41), мы пришли к выводу, что модификация поверхности титановых эндопротезов ведёт к повышению их остеоинтеграции, что снижает риски отторжения конструкций.</p></trans-abstract><kwd-group xml:lang="en"><kwd>titanium alloy</kwd><kwd>endoprosthesis</kwd><kwd>pediatric oncology</kwd><kwd>rehabilitation</kwd><kwd>jaw resection</kwd><kwd>plasma-electrolytic oxidation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>сплав титана</kwd><kwd>эндопротез</kwd><kwd>детская онкология</kwd><kwd>реабилитация</kwd><kwd>резекция челюсти</kwd><kwd>плазменно-электролитическое оксидирование</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Кропотов М.А., Соболевский В.А. Первичные опухоли нижней челюсти. 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