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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Clinical Practice</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Clinical Practice</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиническая практика</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2220-3095</issn><issn publication-format="electronic">2618-8627</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">646054</article-id><article-id pub-id-type="doi">10.17816/clinpract646054</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original Study Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The effects of sarcopenia on the complications after esophagectomy with simultaneous plasty of the esophagus</article-title><trans-title-group xml:lang="ru"><trans-title>Влияние саркопении на осложнения после эзофагэктомии с одномоментной пластикой пищевода</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6951-1816</contrib-id><contrib-id contrib-id-type="spin">2525-9338</contrib-id><name-alternatives><name xml:lang="en"><surname>Kovalerova</surname><given-names>Natalia B.</given-names></name><name xml:lang="ru"><surname>Ковалерова</surname><given-names>Наталья Борисовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук</p></bio><email>kovalerova.nat@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9068-3922</contrib-id><contrib-id contrib-id-type="spin">2587-8568</contrib-id><name-alternatives><name xml:lang="en"><surname>Ruchkin</surname><given-names>Dmitry V.</given-names></name><name xml:lang="ru"><surname>Ручкин</surname><given-names>Дмитрий Валерьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>доктор медицинских наук</p></bio><email>ruchkindmitry@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2537-954X</contrib-id><contrib-id contrib-id-type="spin">4734-0837</contrib-id><name-alternatives><name xml:lang="en"><surname>Strunin</surname><given-names>Oleg V.</given-names></name><name xml:lang="ru"><surname>Струнин</surname><given-names>Олег Всеволодович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>доктор медицинских наук</p></bio><email>struninov@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7460-4884</contrib-id><contrib-id contrib-id-type="spin">2176-2813</contrib-id><name-alternatives><name xml:lang="en"><surname>Okonskaya</surname><given-names>Diana E.</given-names></name><name xml:lang="ru"><surname>Оконская</surname><given-names>Диана Евгеньевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук</p></bio><email>cool_green_alien@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6032-2130</contrib-id><contrib-id contrib-id-type="spin">4446-2220</contrib-id><name-alternatives><name xml:lang="en"><surname>Mazurok</surname><given-names>Alina V.</given-names></name><name xml:lang="ru"><surname>Мазурок</surname><given-names>Алина Вадимовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>alvmazurok@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">A.V. Vishnevsky National Medical Research Center of Surgery</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр хирургии имени А.В. Вишневского</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Russian Medical Academy of Continuous Professional Education</institution></aff><aff><institution xml:lang="ru">Российская медицинская академия непрерывного профессионального образования</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-04-11" publication-format="electronic"><day>11</day><month>04</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-04-30" publication-format="electronic"><day>30</day><month>04</month><year>2025</year></pub-date><volume>16</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>16</fpage><lpage>29</lpage><history><date date-type="received" iso-8601-date="2025-01-14"><day>14</day><month>01</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-03-21"><day>21</day><month>03</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-Вектор</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://clinpractice.ru/clinpractice/article/view/646054">https://clinpractice.ru/clinpractice/article/view/646054</self-uri><abstract xml:lang="en"><p><bold>BACKGROUND</bold><bold>:</bold> Large meta-analyses have proven the negative effects of sarcopenia on the rates of postoperative complications and mortality, on the duration of the postoperative stay at the In-Patient Department and on the 1-, 3- and 5-year survival of the patients. However, given that in coloproctology and emergency surgery, the effects of sarcopenia on the outcomes are undoubtful, in the esophageal surgery the results are extremely controversial. <bold>AIM</bold><bold>:</bold> to evaluate the effects of sarcopenia on the complications in patients after esophagectomy with simultaneous esophageal plasty. <bold>Methods</bold><bold>:</bold> At the National Medical Research Center of Surgery named after A.V. Vishnevsky (NMRCS), a retrospective computed-tomographic diagnostics of sarcopenia was carried out among the patients (n=111) before undergoing esophagectomy with simultaneous esophageal plasty due to the presence of benign or malignant diseases of the esophagus. The perioperative management of all the patients was carried out within the framework of the programs of rationally accelerated perioperative rehabilitation. For the purpose of quantitative evaluation of sarcopenia, the musculoskeletal index was measured. Using the logistic regression, we have evaluated the effects of preoperational sarcopenia on the postoperative complications. <bold>RESULTS</bold><bold>:</bold> Sarcopenia of various degree of intensity was diagnosed in 95 (85.6%) patients. The analysis of the adjusted odds ratios did not reveal any statistically significant relation between sarcopenia and postoperative complications. <bold>CONCLUSION</bold><bold>:</bold> The experience gained at the NMRCS has shown that high-quality surgical technique together with competent perioperative management are able to alleviate the negative effects of sarcopenia on the postoperative complications.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование.</bold> Крупные метаанализы доказали негативное влияние саркопении на частоту послеоперационных осложнений и летальности, длительность послеоперационного пребывания в стационаре и 1-, 3- и 5-летнюю выживаемость пациентов. Однако если в колопроктологии и экстренной хирургии влияние саркопении на исходы не вызывает сомнения, то в хирургии пищевода результаты крайне противоречивы. <bold>Цель исследования</bold> — оценить влияние саркопении на осложнения у пациентов после эзофагэктомии с одномоментной эзофагопластикой. <bold>Методы.</bold> В Национальном медицинском исследовательском центре хирургии им. А.В. Вишневского (НМИЦХ) провели ретроспективную компьютерно-томографическую диагностику саркопении пациентам (n=111) перед эзофагэктомией с одномоментной эзофагопластикой по поводу доброкачественных и злокачественных заболеваний пищевода. Периоперационное обеспечение всех пациентов проходило в рамках программы рационально ускоренной периоперационной реабилитации. Для количественной оценки саркопении измеряли скелетно-мышечный индекс. С помощью логистической регрессии оценили влияние предоперационной саркопении на послеоперационные осложнения. <bold>Результаты. </bold>Саркопению разной степени выраженности диагностировали у 95 (85,6%) пациентов. Анализ скорректированных отношений шансов не выявил статистически значимой ассоциации между саркопенией и послеоперационными осложнениями. <bold>Заключение.</bold> Опыт НМИЦХ показал, что качественная хирургическая техника вкупе с грамотным периоперационным обеспечением способны нивелировать негативное влияние саркопении на послеоперационные осложнения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>sarcopenia</kwd><kwd>esophagectomy</kwd><kwd>esophagoplasty</kwd><kwd>accelerated rehabilitation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>саркопения</kwd><kwd>эзофагэктомия</kwd><kwd>эзофагопластика</kwd><kwd>ускоренная реабилитация</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Rosenberg IH. Sarcopenia: Origins and clinical relevance. 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