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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Clinical Practice</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Clinical Practice</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиническая практика</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2220-3095</issn><issn publication-format="electronic">2618-8627</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">682214</article-id><article-id pub-id-type="doi">10.17816/clinpract682214</article-id><article-id pub-id-type="edn">IXQCVL</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Interdisciplinary challenge of central retinal artery occlusion: a case report</article-title><trans-title-group xml:lang="ru"><trans-title>Тромбоз центральной артерии сетчатки как междисциплинарная проблема: обсуждение клинического случая</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-8485-1729</contrib-id><contrib-id contrib-id-type="spin">1910-2036</contrib-id><name-alternatives><name xml:lang="en"><surname>Polina</surname><given-names>Veronika E.</given-names></name><name xml:lang="ru"><surname>Полина</surname><given-names>Вероника Евгеньевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>dr.polina.v.e@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6061-8118</contrib-id><contrib-id contrib-id-type="spin">7132-9487</contrib-id><name-alternatives><name xml:lang="en"><surname>Kulesh</surname><given-names>Aleksey A.</given-names></name><name xml:lang="ru"><surname>Кулеш</surname><given-names>Алексей Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><email>aleksey.kulesh@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5679-4100</contrib-id><contrib-id contrib-id-type="spin">4127-4022</contrib-id><name-alternatives><name xml:lang="en"><surname>Mekhryakov</surname><given-names>Sergey A.</given-names></name><name xml:lang="ru"><surname>Мехряков</surname><given-names>Сергей Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>heartolog@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2071-9322</contrib-id><contrib-id contrib-id-type="spin">5947-8762</contrib-id><name-alternatives><name xml:lang="en"><surname>Gavrilova</surname><given-names>Tatyana V.</given-names></name><name xml:lang="ru"><surname>Гаврилова</surname><given-names>Татьяна Валерьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor, Corresponding Member of the Russian Academy of Sciences</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, чл.-корр. РАН</p></bio><email>gavrilova.tv@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Academician Ye.A. Vagner Perm State Medical University</institution></aff><aff><institution xml:lang="ru">Пермский государственный медицинский университет имени академика Е.А. Вагнера</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">State Clinical Hospital No. 4, Perm</institution></aff><aff><institution xml:lang="ru">Городская клиническая больница № 4, Пермь</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2026-06-05" publication-format="electronic"><day>05</day><month>06</month><year>2026</year></pub-date><pub-date date-type="pub" iso-8601-date="2026-08-06" publication-format="electronic"><day>06</day><month>08</month><year>2026</year></pub-date><volume>17</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>187</fpage><lpage>195</lpage><history><date date-type="received" iso-8601-date="2025-06-03"><day>03</day><month>06</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2026-02-07"><day>07</day><month>02</month><year>2026</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2026, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2026, Эко-Вектор</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://clinpractice.ru/clinpractice/article/view/682214">https://clinpractice.ru/clinpractice/article/view/682214</self-uri><abstract xml:lang="en"><p><bold>BACKGROUND:</bold> Central retinal artery occlusion, like ischemic stroke, is a serious eye condition characterized by sudden and painless loss of vision in one eye. It is caused by thromboembolism, often secondary to atherosclerosis, and leads to retinal ischemia and necrosis. The visual prognosis for central retinal artery occlusion is poor, and there are no generally accepted treatment guidelines. In most cases, vision does not return, which highlights the need for emergency measures and a comprehensive therapy approach. <bold>CLINICAL CASE DESCRIPTION:</bold> A 71-year-old patient was admitted to the regional stroke response center of City Clinical Hospital No. 4 with sudden vision loss in his right eye and numbness in his left arm. The patient had hypertension and a long smoking history, which increased the risk of vascular complications. Examination revealed critical stenosis (up to 90%) of the right internal carotid artery, indicating a high risk of recurrent embolic events. Since intravenous thrombolysis was contraindicated because of late admission, the patient was initiated on dual-antiplatelet therapy with acetylsalicylic acid and clopidogrel to prevent further thrombosis. Ophthalmological examination confirmed central retinal artery occlusion with a characteristic cherry-red spot and ophthalmic artery non-perfusion. <bold>CONCLUSION:</bold> This case illustrates the importance of early diagnosis and an interdisciplinary approach to treatment of central retinal artery occlusion. Despite the poor visual prognosis, timely therapy and control of risk factors (hypertension, atherosclerosis) can reduce the possibility of recurrent vascular accidents. Optimal management includes emergency hospitalization, neuroimaging, and consultation with a vascular surgeon.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование.</bold> Тромбоз центральной артерии сетчатки — серьёзное офтальмологическое состояние, аналогичное ишемическому инсульту, характеризующееся внезапной и безболезненной потерей зрения на один глаз. Окклюзия центральной артерии сетчатки возникает в результате тромбоэмболии, часто связанной с атеросклерозом, что приводит к ишемии и некрозу сетчатки. Прогноз для зрения при тромбозе центральной артерии сетчатки неблагоприятный, а общепризнанные рекомендации по его лечению отсутствуют. В большинстве случаев зрение не восстанавливается, что подчёркивает необходимость экстренных мер и комплексного подхода к терапии. <bold>Описание клинического случая.</bold> Наблюдали 71-летнего пациента, который поступил в региональный сосудистый центр ГКБ № 4 с резкой потерей зрения на правый глаз и онемением левой руки. В анамнезе у пациента гипертоническая болезнь и длительный стаж курения, что увеличивало риск сосудистых осложнений. При обследовании выявлен критический стеноз правой внутренней сонной артерии до 90%, что указывало на высокий риск повторных эмболических событий. Из-за противопоказаний к внутривенному тромболизису (позднее обращение) пациенту была назначена двойная антитромбоцитарная терапия (ацетилсалициловая кислота и клопидогрел) для профилактики дальнейших тромбозов. Офтальмологическое обследование подтвердило окклюзию центральной артерии сетчатки с характерным симптомом «вишнёвой косточки» и отсутствием кровотока в глазной артерии. <bold>Заключение.</bold> Данный случай иллюстрирует важность ранней диагностики и междисциплинарного подхода в лечении тромбоза центральной артерии сетчатки. Несмотря на неблагоприятный прогноз для зрения, своевременная терапия и контроль факторов риска (гипертония, атеросклероз) позволяют снизить вероятность повторных сосудистых катастроф. Оптимальная тактика включает экстренную госпитализацию, нейровизуализацию и консультацию сосудистого хирурга.</p></trans-abstract><kwd-group xml:lang="en"><kwd>central retinal artery occlusion</kwd><kwd>sudden vision loss</kwd><kwd>thromboembolism</kwd><kwd>atherosclerosis</kwd><kwd>case report</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>тромбоз центральной артерии сетчатки</kwd><kwd>внезапная потеря зрения</kwd><kwd>тромбоэмболия</kwd><kwd>атеросклероз</kwd><kwd>клинический случай</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Mac Grory B, Schrag M, Biousse V, et al. Management of central retinal artery occlusion: a scientific statement from the American Heart Association. Stroke. 2021;52(6):e282–e294. doi: 10.1161/STR.0000000000000366 EDN: PELNNP</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Baldoncini M, Campero A, Moran G, et al. 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