电邮这篇文章 Structure of acute chemical poisoning during COVID-19 pandemic (according to a multidiscipline hospital)
- 作者: Lodyagin A.N.1, Sinenchenko A.G.1, Shilov V.V.1, Batotsyrenov B.V.1, Sinenchenko G.I.1
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隶属关系:
- St. Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine
- 期: 编号 1 (2022)
- 页面: 4-11
- 栏目: Original articles
- ##submission.datePublished##: 17.02.2022
- URL: https://clinpractice.ru/0869-7922/article/view/641387
- DOI: https://doi.org/10.47470/0869-7922-2022-30-1-4-11
- ID: 641387
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Introduction. The article presents an epidemiological analysis of the prevalence and structure of acute chemical poisoning in the Northwestern region during the Covid-19 pandemic. The purpose of the study: to analyze the prevalence and structure of acute chemical poisoning among patients of a multidisciplinary hospital during the Covid-19 pandemic.
Materials and methods. In the course of the work, archival, monthly statistical data were used on the registration of persons hospitalized in the center for the treatment of acute poisoning of the named after I.I. Dzhanelidze Research Institute of SP in the period 2019–2020. The main method of the study was clinical and epidemiological, which includes an analysis of the intra-annual dynamics of the occurrence of acute chemical poisoning, based on monthly observations. In the statistical processing of the material, numerical characteristics of variables with an assessment of their accuracy and reliability were used, analytical methods aimed at constructing a time series model by autoregression and integrated moving average (ARIMA) were used. Nominal data were compared using the criterion χ2 adjusted for continuity.
Results. The epidemiological analysis revealed the main trends indicating a decrease in the total number of admissions of patients with acute chemical poisoning to a multidisciplinary hospital during the Covid-19 pandemic (y = –106.25x + 17.16, R2 = 0.7346). The data obtained indicate, first of all, a decrease in the income of persons with acute alcohol poisoning and higher alcohols, starting from April 2020, which, of course, was facilitated by the introduction of a strictly anti-epidemic regime in the GBU Research Institute of SP named after I.I. Dzhanelidze and the change in the conditions of hospitalization in medical institutions of St. Petersburg during the Covid-19 pandemic. The increase in the frequency of acute poisoning with medicinal substances (antipyretics, analgesics and sedatives) used for the purpose of self-treatment of the main symptoms of an infectious disease has attracted attention. The main problem for public health remains the increase in the number of cases of acute poisoning with narcotic substances from the group of synthetic cathinones, synthetic derivatives of opium, precursors of gamma-hydroxyoximabutyric acid.
Conclusion. Data on the prevalence of acute chemical poisoning during the Covid-19 pandemic (according to the multidisciplinary hospital) indicate changes in the frequency of their occurrence and structure.
An increase in cases of admission of persons with poisoning with analgesics, antipyretics, psychotropic drugs with sedative effect was found in the analyzed time period.
作者简介
Aleksei Lodyagin
St. Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine
编辑信件的主要联系方式.
Email: noemail@neicon.ru
ORCID iD: 0000-0002-8672-2906
Доктор медицинских наук, профессор, руководитель отдела клинической токсикологии ГБУ «СПб НИИ скорой помощи им. И.И. Джанелидзе», 192242, Санкт-Петербург
俄罗斯联邦Andrei Sinenchenko
St. Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine
Email: andreysin2013@yandes.ru
ORCID iD: 0000-0003-2815-3108
PhD, head of the department of emergency psychiatry, narcology and psychorehabilitation, the St. Petersburg named after I.I. Dzhanelidze Research Institute of Emergency Medicine, 192242, St. Petersburg, Russian Federation.
e-mail: andreysin2013@yandex.ru
俄罗斯联邦Viktor Shilov
St. Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine
Email: vshilov@inbox.ru
ORCID iD: 0000-0003-3256-2609
Главный научный сотрудник отдела клинической токсикологии, доктор медицинских наук, профессор.
e-mail: vshilov@inbox.ru
俄罗斯联邦Bair Batotsyrenov
St. Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine
Email: bbair@mail.ru
ORCID iD: 0000-0003-4954-8977
Доктор медицинских наук, доцент, главный научный сотрудник отдела клинической токсикологии ГБУ «СПб НИИ скорой помощи им. И.И. Джанелидзе», 192242, Санкт-Петербург.
e-mail: bbair@mail.ru
俄罗斯联邦Georgi Sinenchenko
St. Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine
Email: andreysin2013@yandex.ru
ORCID iD: 0000-0001-5659-781X
Заслуженный врач РФ, доктор медицинских наук, профессор, преподаватель ГБУ «СПб НИИ скорой помощи им. И.И. Джанелидзе», 192242, Санкт-Петербург.
e-mail: andreysin2013@yandex.ru
俄罗斯联邦参考
- Peng M. Outbreak of COVID-19: An emerging global pandemic threat. Biomed Pharmacother. 2020; 129: 110499. https://doi.org/10.1016/j.biopha.2020.110499
- Zhai P., Ding Y., Wu X., Long J., Zhong Y., Li Y. Int J Antimicrob Agents. Int J. 2020; 55(5): 105955. https://doi.org/10.1016/j.ijantimicag.2020.105955
- Zhang L.P., Wang M., Wang Y., Zhu J., Zhang N. Focus on the 2019 novel coronavirus (SARS-CoV-2). Future Microbiol. 2020 Jul; 15: 905-918. https://doi.org/10.2217/fmb-2020-0063
- Gao Z., Xu Y., Sun C., Wang X., Guo Y., Qiu S., Ma K. A systematic review of asymptomatic infections with COVID-19. J Microbiol Immunol Infect. 2021; 54(1): 12-16. https://10.1016/j.jmii.2020.05.001
- Ahn D.G., Shin H.J., Kim M.H., Lee S., Kim H.S., Myoung J. [et al] Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for Novel Coronavirus Disease 2019 (COVID-19). J Microbiol Biotechnol. 2020; 30(3): 313-24. https://doi.org/10.4014/jmb.2003.03011
- Salajegheh Tazerji S., Magalhães Duarte P., Rahimi P., Shahabinejad F., Dhakal S., et al. Transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to animals: an updated review. J Transl Med. 2020; 18(1): 358. https://doi.org/10.1186/s12967-020-02534-2
- Kovalev E.V., Sly S.S., Yanovich E.G., Pichurina N.L., Volovikova S.V. et al. Some features of the epidemic spread of a new coronavirus infection (covid-19) in the Rostov region. Medical Bulletin of the South of Russia. 2020; 11(4): 99-106. https://doi.org/10.21886/2219-8075-2020-11-4-99-106 (in Russian)
- Harapan H., Itoh N., Yufika A., Winardi W., Keam S., Te H. et al. Coronavirus disease 2019 (COVID-19): A literature review. J Infect Public Health. 2020; 13(5): 667-73. https://doi.org/10.1016/j.jiph.2020.03.019
- Medvedev V.E., Dogotar O.A. Covid-19 and mental health: challenges and first conclusions. Neurology, neuropsychiatry, psychosomatics. 2020; 12(6): 4-10. https://doi.org/10.14412/2074-2711-2020-6-4-10 (in Russian)
- Mahmood A., Eqan M., Pervez S., Alghamdi H.A., Tabinda A.B. et al. COVID-19 and frequent use of hand sanitizers; human health and environmental hazards by exposure pathways. Sci Total Environ. PMID: 32623176. PMCID: PMC7320712. https://doi.org/10.1016/j.scitotenv.2020.140561
- Li C., Cheng G. Hydroxychloroquine Still Be a Game-Changer for Covid-19 by Combining Azithromycin? Front Immunol. 2020; 11: 1969. https://doi.org/10.3389/fimmu.2020.01969
- Okour M., Al-Kofahi M., Austin D. Hydroxychloroquine and azithromycin as potential treatments for COVID-19; clinical status impacts the outcome. J Pharmacokinet Pharmacodyn. 2020; 47(3): 187-8. https://dopi.org/10.1007/s10928-020-09689-x
- Bilichenko T.N. Epidemiologiya novoj koronavirusnoj infekcii (COVID-19). Akademiya mediciny i sporta. 2020; 1(2): 14-20. https://doi.org/10.15829/1560-4071-2020-2-15 (in Russian)
- Milella M.S., Boldrini P., Vivino G., Grassi M.C. How COVID-19 Lockdown in Italy Has Affected Type of Calls and Management of Toxic Exposures: a Retrospective Analysis of a Poison Control Center Database From March 2020 to May 2020. J Med Toxicol. 2021; 17(3): 250-6. https://doi.org/10.1007/s13181-021-00839-2
- Soave P.M., Grassi S., Oliva A., Romanò B., Di Stasio E. et al. Household disinfectant exposure during the COVID-19 pandemic: a retrospective study of the data from an Italian poison control center. Eur Rev Med Pharmacol Sci. 2021; 25(3): 1738-42. https://doi.org/10.26355/eurrev_202102_24884
- Le Roux G., Sinno-Tellier S., French Poison Control Centre members, Descatha A. COVID-19: home poisoning throughout the containment period. Lancet Public Health. 2020; 5(6): e314. https://doi.org/10.1016/S2468-2667(20)30095-5
- Belova M.V., Ilyashenko K.K., Simonova A.Yu., Potshveria M.M., Trusov G.V. The structure of acute exotoxicoses in the first three months of the Covid-19 pandemic (according to the Department of Acute poisoning of the State Medical Institution “N.V. Sklifosovsky Research Institute of Emergency Medicine”). Emergency medical caremeditsinskaya pomoshch. Neotlozhonaya meditsinskaya pomoshch. Zurnal im. N.V. Sklifosovskogo. 2020; 10(1): 27-32. https://doi.org/10.23934/2223-9022-2021-10-1-27-32 (in Russian)
- Fayed M.M., Sharif A.F. Impact of Lockdown due to COVID-19 on the Modalities of Intoxicated Patients Presenting to the Emergency Room. Prehosp Disaster Med. 2021; 36(2): 145-62. https://doi.org/10.1017/S1049023X20001533
- Klimenko T.V., Kozlov A.A., Igumnov S.A., Fastovtsov G.A., Zborovsky K.E., Iskan-darov R.R. Narcological disorders in the era of the Covid-19 pandemic. Voennaya medicina. 2021; 1: 94-104. (in Russian)
- Lipanova L.L., Nasybullin G.M., Kazantsev V.S. Prevalence of psychoactive substances consumption by schoolchildren and multifactorial analysis of the causes of alcohol and tobacco addiction. Profilakticheskaya i klinicheskaya medicina. 2019; 1(70): 4-9. (in Russian)
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