Determination of the Microelement Composition of Biopsy Material of Red Bone Marrow in Patients with Hemoblastoses by the SR–XRF Method
- 作者: Trunova V.A.1,2, Pospelova T.I.3, Voytko M.S.3, Krupovich E.S.1,4, Soldatova G.S.3,2, Kuzmin R.O.3, Tsigulyov K.S.3
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隶属关系:
- Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences
- Novosibirsk State University
- Novosibirsk State Medical University
- Institute of Catalysis of the Siberian Branch of the Russian Academy of Sciences
- 期: 编号 2 (2025)
- 页面: 124-130
- 栏目: Articles
- URL: https://clinpractice.ru/1028-0960/article/view/686840
- DOI: https://doi.org/10.31857/S1028096025020154
- EDN: https://elibrary.ru/EILIRG
- ID: 686840
如何引用文章
详细
Personalized medicine is a modern concept aimed at individualization of patient therapy. The relevance of the search and identification of new highly sensitive and specific prognostic markers in patients with hemoblastoses is due to the leading positions in the incidence and mortality rate among young working-age population, which gives the problem special socio-economic significance. The study is aimed at studying the content of trace elements in biopsy material (red bone marrow) of patients with hemoblastoses at the onset of the disease and after chemoradiation therapy. Using the method of X-ray fluorescence analysis and synchrotron radiation, it is possible to simultaneously determine more than 25 chemical elements in a low-mass sample with non-destructive sample preparation. Difference in the concentrations of 10 elements (S, K, Ca, Cu, Zn, Fe, Se, Br, Rb, Cd) in patients with two pathologies, lymphoma and leukemia, is considered.
全文:

作者简介
V. Trunova
Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences; Novosibirsk State University
编辑信件的主要联系方式.
Email: valna-t@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk
T. Pospelova
Novosibirsk State Medical University
Email: valna-t@mail.ru
俄罗斯联邦, Novosibirsk
M. Voytko
Novosibirsk State Medical University
Email: valna-t@mail.ru
俄罗斯联邦, Novosibirsk
E. Krupovich
Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences; Institute of Catalysis of the Siberian Branch of the Russian Academy of Sciences
Email: valna-t@mail.ru
俄罗斯联邦, Novosibirsk; Koltsovo
G. Soldatova
Novosibirsk State Medical University; Novosibirsk State University
Email: valna-t@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk
R. Kuzmin
Novosibirsk State Medical University
Email: valna-t@mail.ru
俄罗斯联邦, Novosibirsk
K. Tsigulyov
Novosibirsk State Medical University
Email: valna-t@mail.ru
俄罗斯联邦, Novosibirsk
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